The Lab · 2026 season
Week 5 matchups
Every game on the slate, broken into eight pairings: each offense against the other team’s defense, one position group at a time. Open any game for the numbers, the players, the coaches and who is missing.
Raiders at Patriots
Sun, Oct 11 · 1:00 PM ET
Patriots favored by 3.5 · over/under 45.5
40pairings with the edge, out of 8
The biggest mismatch: the Raiders pass rush (2nd) against the Patriots pass protection (25th).
- Raiders: Raiders pass rush (2nd) against the Patriots pass protection (25th)
Buccaneers at Cowboys
Thu, Oct 8 · 8:15 PM ET
Cowboys favored by 8.5 · over/under 47.5
34pairings with the edge, out of 8
The biggest mismatch: the Cowboys pass protection (15th) against the Buccaneers pass rush (30th).
- Buccaneers: Buccaneers receiving corps (23rd) against the Cowboys pass coverage (32nd)
- Cowboys: Cowboys pass protection (15th) against the Buccaneers pass rush (30th)
Eagles at Jaguars
Sun, Oct 11 · 9:30 AM ET
Jaguars favored by 7 · over/under 42.5
08pairings with the edge, out of 8
The biggest mismatch: the Jaguars pass protection (20th) against the Eagles pass rush (31st).
- Jaguars: Jaguars pass protection (20th) against the Eagles pass rush (31st)
Bears at Packers
Sun, Oct 11 · 1:00 PM ET
Bears favored by 2.5 · over/under 45.5
50pairings with the edge, out of 8
The biggest mismatch: the Bears pass coverage (4th) against the Packers quarterback play (23rd).
- Bears: Bears pass coverage (4th) against the Packers quarterback play (23rd)
Bengals at Dolphins
Sun, Oct 11 · 1:00 PM ET
Bengals favored by 6.5 · over/under 42.5
51pairings with the edge, out of 8
The biggest mismatch: the Bengals pass rush (6th) against the Dolphins pass protection (31st).
- Bengals: Bengals pass rush (6th) against the Dolphins pass protection (31st)
- Dolphins: Dolphins run defense (3rd) against the Bengals run game (20th)
Vikings at Saints
Sun, Oct 11 · 1:00 PM ET
Vikings favored by 1.5 · over/under 42.5
71pairings with the edge, out of 8
The biggest mismatch: the Vikings pass coverage (1st) against the Saints quarterback play (17th).
- Vikings: Vikings pass coverage (1st) against the Saints quarterback play (17th)
- Saints: Saints pass rush (19th) against the Vikings pass protection (28th)
Browns at Jets
Sun, Oct 11 · 1:00 PM ET
Jets favored by 1.5 · over/under 39.5
41pairings with the edge, out of 8
The biggest mismatch: the Browns receiving corps (2nd) against the Jets pass coverage (16th).
- Browns: Browns receiving corps (2nd) against the Jets pass coverage (16th)
- Jets: Jets quarterback play (5th) against the Browns pass coverage (12th)
Colts at Steelers
Sun, Oct 11 · 1:00 PM ET
Steelers favored by 2.5 · over/under 44.5
14pairings with the edge, out of 8
The biggest mismatch: the Steelers pass coverage (14th) against the Colts quarterback play (30th).
- Colts: Colts run game (9th) against the Steelers run defense (22nd)
- Steelers: Steelers pass coverage (14th) against the Colts quarterback play (30th)
Texans at Titans
Sun, Oct 11 · 1:00 PM ET
Texans favored by 7.5 · over/under 37.5
32pairings with the edge, out of 8
The biggest mismatch: the Titans run defense (7th) against the Texans run game (32nd).
- Texans: Texans quarterback play (9th) against the Titans pass coverage (29th)
- Titans: Titans run defense (7th) against the Texans run game (32nd)
Giants at Commanders
Sun, Oct 11 · 1:00 PM ET
Commanders favored by 3.5 · over/under 42.5
23pairings with the edge, out of 8
The biggest mismatch: the Commanders pass protection (13th) against the Giants pass rush (32nd).
- Giants: Giants pass coverage (8th) against the Commanders receiving corps (32nd)
- Commanders: Commanders pass protection (13th) against the Giants pass rush (32nd)
Broncos at Chargers
Sun, Oct 11 · 4:05 PM ET
Broncos favored by 3.5 · over/under 41.5
42pairings with the edge, out of 8
The biggest mismatch: the Broncos pass coverage (7th) against the Chargers quarterback play (31st).
- Broncos: Broncos pass coverage (7th) against the Chargers quarterback play (31st)
- Chargers: Chargers run game (13th) against the Broncos run defense (31st)
Lions at Cardinals
Sun, Oct 11 · 4:25 PM ET
Lions favored by 5.5 · over/under 54.5
33pairings with the edge, out of 8
The biggest mismatch: the Lions receiving corps (17th) against the Cardinals pass coverage (31st).
- Lions: Lions receiving corps (17th) against the Cardinals pass coverage (31st)
- Cardinals: Cardinals receiving corps (27th) against the Lions pass coverage (30th)
49ers at Seahawks
Sun, Oct 11 · 4:25 PM ET
Seahawks favored by 2.5 · over/under 45.5
22pairings with the edge, out of 8
The biggest mismatch: the Seahawks quarterback play (6th) against the 49ers pass coverage (21st).
- 49ers: 49ers run defense (14th) against the Seahawks run game (25th)
- Seahawks: Seahawks quarterback play (6th) against the 49ers pass coverage (21st)
Ravens at Falcons
Sun, Oct 11 · 8:20 PM ET
Falcons favored by 3.5 · over/under 43.5
42pairings with the edge, out of 8
The biggest mismatch: the Ravens quarterback play (1st) against the Falcons pass coverage (17th).
- Ravens: Ravens quarterback play (1st) against the Falcons pass coverage (17th)
- Falcons: Falcons run game (2nd) against the Ravens run defense (16th)
Bills at Rams
Mon, Oct 12 · 8:15 PM ET
Rams favored by 3 · over/under 54.5
25pairings with the edge, out of 8
The biggest mismatch: the Rams run game (5th) against the Bills run defense (17th).
- Bills: Bills run game (1st) against the Rams run defense (9th)
- Rams: Rams run game (5th) against the Bills run defense (17th)
Data: nflverse play-by-play, CC BY 4.0. Ranks use the 2026 regular season through Week 4. Lines are the opening spreads in the games file. Also FTN charting, Pro Football Reference advanced stats, snap counts and injury reports, all through nflverse. Calculations and charts by Raiders Rundown.